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Targeting genetic alterations in protein methyltransferases for personalized cancer therapeutics

The human protein methyltransferases (PMTs) constitute a large enzyme class composed of two families, the protein lysine methyltransferases (PKMTs) and the protein arginine methyltransferases (PRMTs). Examples have been reported of both PKMTs and PRMTs that are genetically altered in specific human...

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Detalles Bibliográficos
Autores principales: Copeland, R A, Moyer, M P, Richon, V M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579158/
https://www.ncbi.nlm.nih.gov/pubmed/23160372
http://dx.doi.org/10.1038/onc.2012.552