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The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway

OBJECTIVE: To examine if leisure-time physical activity could cancel out the adverse effect of diabetes on cardiovascular mortality. RESEARCH DESIGN AND METHODS: This study prospectively examined the combined effect of clinical diabetes and reported leisure-time physical activity on cardiovascular m...

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Autores principales: Moe, Børge, Eilertsen, Eivin, Nilsen, Tom I.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579362/
https://www.ncbi.nlm.nih.gov/pubmed/23160724
http://dx.doi.org/10.2337/dc11-2472
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author Moe, Børge
Eilertsen, Eivin
Nilsen, Tom I.L.
author_facet Moe, Børge
Eilertsen, Eivin
Nilsen, Tom I.L.
author_sort Moe, Børge
collection PubMed
description OBJECTIVE: To examine if leisure-time physical activity could cancel out the adverse effect of diabetes on cardiovascular mortality. RESEARCH DESIGN AND METHODS: This study prospectively examined the combined effect of clinical diabetes and reported leisure-time physical activity on cardiovascular mortality. Data on 53,587 Norwegian men and women participating in the population-based Nord-Trøndelag Health (HUNT) Study (1995–1997) were linked with the Cause of Death Registry at Statistics Norway. RESULTS: Overall, 1,716 people died of cardiovascular disease during follow-up through 2008. Compared with the reference group of 3,077 physically inactive people without diabetes, 121 inactive people with diabetes had an adjusted hazard ratio (HR) of 2.81 (95% CI 1.93–4.07). The HR (95% CI) among people who reported ≥3 h of light activity per week was 0.89 (0.48–1.63) if they had diabetes (n = 403) and 0.78 (0.63–0.96) if they did not (n = 17,714). Analyses stratified by total activity level showed a gradually weaker association of diabetes with mortality with increasing activity level (P(interaction) = 0.003). CONCLUSIONS: The data suggest that even modest physical activity may cancel out the adverse impact of diabetes on cardiovascular mortality.
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spelling pubmed-35793622014-03-01 The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway Moe, Børge Eilertsen, Eivin Nilsen, Tom I.L. Diabetes Care Original Research OBJECTIVE: To examine if leisure-time physical activity could cancel out the adverse effect of diabetes on cardiovascular mortality. RESEARCH DESIGN AND METHODS: This study prospectively examined the combined effect of clinical diabetes and reported leisure-time physical activity on cardiovascular mortality. Data on 53,587 Norwegian men and women participating in the population-based Nord-Trøndelag Health (HUNT) Study (1995–1997) were linked with the Cause of Death Registry at Statistics Norway. RESULTS: Overall, 1,716 people died of cardiovascular disease during follow-up through 2008. Compared with the reference group of 3,077 physically inactive people without diabetes, 121 inactive people with diabetes had an adjusted hazard ratio (HR) of 2.81 (95% CI 1.93–4.07). The HR (95% CI) among people who reported ≥3 h of light activity per week was 0.89 (0.48–1.63) if they had diabetes (n = 403) and 0.78 (0.63–0.96) if they did not (n = 17,714). Analyses stratified by total activity level showed a gradually weaker association of diabetes with mortality with increasing activity level (P(interaction) = 0.003). CONCLUSIONS: The data suggest that even modest physical activity may cancel out the adverse impact of diabetes on cardiovascular mortality. American Diabetes Association 2013-03 2013-02-13 /pmc/articles/PMC3579362/ /pubmed/23160724 http://dx.doi.org/10.2337/dc11-2472 Text en © 2013 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0/ for details.
spellingShingle Original Research
Moe, Børge
Eilertsen, Eivin
Nilsen, Tom I.L.
The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title_full The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title_fullStr The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title_full_unstemmed The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title_short The Combined Effect of Leisure-Time Physical Activity and Diabetes on Cardiovascular Mortality: The Nord-Trøndelag Health (HUNT) cohort study, Norway
title_sort combined effect of leisure-time physical activity and diabetes on cardiovascular mortality: the nord-trøndelag health (hunt) cohort study, norway
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579362/
https://www.ncbi.nlm.nih.gov/pubmed/23160724
http://dx.doi.org/10.2337/dc11-2472
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