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Incretin secretion stimulated by ursodeoxycholic acid in healthy subjects
Bile acids play an important role in post-prandial glucose metabolism by stimulating release of glucagon-like peptide-1 (GLP-1) via the G-protein-coupled receptor TGR5, which is expressed in intestinal L cells. Thus, bile acid sequestrants are expected to stimulate secretion of endogenous GLP-1 thro...
Autores principales: | Murakami, Masanori, Une, Naoko, Nishizawa, Maiko, Suzuki, Sayaka, Ito, Hideki, Horiuchi, Toshiyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing AG
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579475/ https://www.ncbi.nlm.nih.gov/pubmed/23450079 http://dx.doi.org/10.1186/2193-1801-2-20 |
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