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Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma
BACKGROUND: Palmitoylethanolamide (PEA) is an endogenous fatty acid amide displaying anti-inflammatory and analgesic actions. Moreover, several data have suggested that PEA reduced inflammation and tissue injury associated with spinal cord trauma and showed a regulatory role for peroxisome prolifera...
Autores principales: | Paterniti, Irene, Impellizzeri, Daniela, Crupi, Rosalia, Morabito, Rossana, Campolo, Michela, Esposito, Emanuela, Cuzzocrea, Salvatore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579707/ https://www.ncbi.nlm.nih.gov/pubmed/23374874 http://dx.doi.org/10.1186/1742-2094-10-20 |
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