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Steerable-filter based quantification of axonal populations at the developing optic chiasm reveal significant defects in Slit2(−/−) as well as Slit1(−/−)Slit2(−/−) embryos
BACKGROUND: Previous studies have suggested that the axon guidance proteins Slit1 and Slit2 co-operate to establish the optic chiasm in its correct position at the ventral diencephalic midline. This is based on the observation that, although both Slit1 and Slit2 are expressed around the ventral midl...
Autores principales: | Down, Matthew, Willshaw, David A, Pratt, Thomas, Price, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579723/ https://www.ncbi.nlm.nih.gov/pubmed/23320558 http://dx.doi.org/10.1186/1471-2202-14-9 |
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