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Antibody-Mediated Activation of FGFR1 Induces FGF23 Production and Hypophosphatemia

The phosphaturic hormone Fibroblast Growth Factor 23 (FGF23) controls phosphate homeostasis by regulating renal expression of sodium-dependent phosphate co-transporters and cytochrome P450 enzymes involved in vitamin D catabolism. Multiple FGF Receptors (FGFRs) can act as receptors for FGF23 when bo...

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Detalles Bibliográficos
Autores principales:	Wu, Ai-Luen, Feng, Bo, Chen, Mark Z., Kolumam, Ganesh, Zavala-Solorio, Jose, Wyatt, Shelby K., Gandham, Vineela D., Carano, Richard A. D., Sonoda, Junichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579827/ https://www.ncbi.nlm.nih.gov/pubmed/23451204 http://dx.doi.org/10.1371/journal.pone.0057322

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