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Tyrosine-1 and threonine-4 phosphorylation marks complete the RNA polymerase II CTD phospho-code

Eukaryotic RNA polymerase II (RNAP II) has evolved an array of heptad repeats with the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7 at the carboxy-terminal domain (CTD) of its largest subunit (Rpb1). Dynamic phosphorylation of Ser2, Ser5 and Ser7 residues orchestrates the binding of transcr...

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Detalles Bibliográficos
Autores principales:	Heidemann, Martin, Eick, Dirk
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Point of View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579880/ https://www.ncbi.nlm.nih.gov/pubmed/22960391 http://dx.doi.org/10.4161/rna.21726

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