High-Throughput Screening for Growth Inhibitors Using a Yeast Model of Familial Paraganglioma

Classical tumor suppressor genes block neoplasia by regulating cell growth and death. A remarkable puzzle is therefore presented by familial paraganglioma (PGL), a neuroendocrine cancer where the tumor suppressor genes encode subunits of succinate dehydrogenase (SDH), an enzyme of the tricarboxylic...

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Detalles Bibliográficos
Autores principales: Bancos, Irina, Bida, John Paul, Tian, Defeng, Bundrick, Mary, John, Kristen, Holte, Molly Nelson, Her, Yeng F., Evans, Debra, Saenz, Dyana T., Poeschla, Eric M., Hook, Derek, Georg, Gunda, Maher, L. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579935/
https://www.ncbi.nlm.nih.gov/pubmed/23451094
http://dx.doi.org/10.1371/journal.pone.0056827

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