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Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

Objective Cerebral atrophy is a correlate of clinical progression in multiple sclerosis (MS). Mitochondria are now established to play a part in the pathogenesis of MS. Uniquely, mitochondria harbor their own mitochondrial DNA (mtDNA), essential for maintaining a healthy central nervous system. We e...

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Detalles Bibliográficos
Autores principales:	Campbell, Graham R, Ziabreva, Iryna, Reeve, Amy K, Krishnan, Kim J, Reynolds, Richard, Howell, Owen, Lassmann, Hans, Turnbull, Doug M, Mahad, Don J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580047/ https://www.ncbi.nlm.nih.gov/pubmed/21446022 http://dx.doi.org/10.1002/ana.22109

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