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Derivation of HLA types from shotgun sequence datasets
The human leukocyte antigen (HLA) is key to many aspects of human physiology and medicine. All current sequence-based HLA typing methodologies are targeted approaches requiring the amplification of specific HLA gene segments. Whole genome, exome and transcriptome shotgun sequencing can generate prod...
Autores principales: | Warren, René L, Choe, Gina, Freeman, Douglas J, Castellarin, Mauro, Munro, Sarah, Moore, Richard, Holt, Robert A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580435/ https://www.ncbi.nlm.nih.gov/pubmed/23228053 http://dx.doi.org/10.1186/gm396 |
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