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Secretome analysis of chondroitin sulfate-treated chondrocytes reveals anti-angiogenic, anti-inflammatory and anti-catabolic properties

INTRODUCTION: Chondroitin sulfate (CS) is a symptomatic slow-acting drug for osteoarthritis (OA) widely used in the clinic. The aim of this work is to find proteins whose secretion from cartilage cells under proinflammatory stimuli (IL-1β) is regulated by CS, employing a novel quantitative proteomic...

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Detalles Bibliográficos
Autores principales:	Calamia, Valentina, Lourido, Lucía, Fernández-Puente, Patricia, Mateos, Jesús, Rocha, Beatriz, Montell, Eulalia, Vergés, Josep, Ruiz-Romero, Cristina, Blanco, Francisco J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580514/ https://www.ncbi.nlm.nih.gov/pubmed/23031212 http://dx.doi.org/10.1186/ar4040

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