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Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes

INTRODUCTION: Insulin-like growth factor I (IGF-I) regulates articular cartilage homeostasis. During osteoarthritis (OA), the anabolic responses of chondrocytes to IGF-I are likely to be prevented by the enhanced production of IGF-binding proteins (IGFBPs), especially IGFBP-3. The aim of this study...

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Detalles Bibliográficos
Autores principales:	Gasparini, Giorgio, De Gori, Marco, Paonessa, Francesco, Chiefari, Eusebio, Brunetti, Antonio, Galasso, Olimpio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580519/ https://www.ncbi.nlm.nih.gov/pubmed/23036517 http://dx.doi.org/10.1186/ar4045

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