Cargando…

Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes

INTRODUCTION: Rheumatoid arthritis (RA) is characterized by progressive inflammation associated with rampantly proliferating synoviocytes and joint destruction due to oxidative stress. Recently, we described nuclear factor erythroid 2-related factor 2 (Nrf2) as a major requirement for limiting carti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fragoulis, Athanassios, Laufs, Jendrik, Müller, Susanna, Soppa, Ulf, Siegl, Stephanie, Reiss, Lucy Kathleen, Tohidnezhad, Mersedeh, Rosen, Christian, Tenbrock, Klaus, Varoga, Deike, Lippross, Sebastian, Pufe, Thomas, Wruck, Christoph Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580531/ https://www.ncbi.nlm.nih.gov/pubmed/23072510 http://dx.doi.org/10.1186/ar4059

Ejemplares similares

Platelet-Released Growth Factors Modulate the Secretion of Cytokines in Synoviocytes under Inflammatory Joint Disease
por: Tohidnezhad, Mersedeh, et al.
Publicado: (2017)

Hepatocytes express the antimicrobial peptide HBD-2 after multiple trauma: an experimental study in human and mice
por: Fitschen-Oestern, Stefanie, et al.
Publicado: (2017)

The Antimicrobial Peptide Lysozyme Is Induced after Multiple Trauma
por: Klüter, Tim, et al.
Publicado: (2014)

A new multiple trauma model of the mouse
por: Fitschen-Oestern, Stefanie, et al.
Publicado: (2017)

Correction to: A new multiple trauma model of the mouse
por: Fitschen-Oestern, Stefanie, et al.
Publicado: (2019)

Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease
por: Fragoulis, Athanassios, et al.
Publicado: (2017)

The Contribution of the Nrf2/ARE System to Mechanotransduction in Musculoskeletal and Periodontal Tissues
por: Fragoulis, Athanassios, et al.
Publicado: (2023)

Abrasion arthroplasty increases mesenchymal stem cell content of postoperative joint effusions
por: Beckmann, Rainer, et al.
Publicado: (2015)

Mechanical Forces Induce Changes in VEGF and VEGFR-1/sFlt-1 Expression in Human Chondrocytes
por: Beckmann, Rainer, et al.
Publicado: (2014)

Reactive oxygen species induce expression of vascular endothelial growth factor in chondrocytes and human articular cartilage explants
por: Fay, Jakob, et al.
Publicado: (2006)

Sulforaphane Exerts Beneficial Immunomodulatory Effects on Liver Tissue via a Nrf2 Pathway-Related Mechanism in a Murine Model of Hemorrhagic Shock and Resuscitation
por: Liang, Weiqiang, et al.
Publicado: (2022)

A Novel Laser-Doppler Flowmetry Assisted Murine Model of Acute Hindlimb Ischemia-Reperfusion for Free Flap Research
por: Sönmez, Tolga Taha, et al.
Publicado: (2013)

Nrf2 Protects Against TWEAK-mediated Skeletal Muscle Wasting
por: Al-Sawaf, Othman, et al.
Publicado: (2014)

Rivaroxaban does not impair fracture healing in a rat femur fracture model: an experimental study
por: Klüter, Tim, et al.
Publicado: (2015)

Platelet-Released Growth Factors Induce Differentiation of Primary Keratinocytes
por: Bayer, Andreas, et al.
Publicado: (2017)

The Antimicrobial Peptide Human Beta-Defensin-3 Is Induced by Platelet-Released Growth Factors in Primary Keratinocytes
por: Bayer, Andreas, et al.
Publicado: (2017)

Local pamidronate influences fracture healing in a rodent femur fracture model: an experimental study
por: Menzdorf, Leif, et al.
Publicado: (2016)

The formyl peptide receptor like-1 and scavenger receptor MARCO are involved in glial cell activation in bacterial meningitis
por: Braun, Benedikt J, et al.
Publicado: (2011)

Nuclear factor erythroid 2–related factor 2 (Nrf2) deficiency causes age-dependent progression of female osteoporosis
por: Kubo, Yusuke, et al.
Publicado: (2022)

Effect of platelet mediator concentrate (PMC) on Achilles tenocytes: an in vitro study
por: Arslan, Esra, et al.
Publicado: (2016)

Nrf2/ARE Signaling Directly Regulates SOX9 to Potentially Alter Age-Dependent Cartilage Degeneration
por: Kubo, Yusuke, et al.
Publicado: (2022)

Effects of Strontium-Doped β-Tricalcium Scaffold on Longitudinal Nuclear Factor-Kappa Beta and Vascular Endothelial Growth Factor Receptor-2 Promoter Activities during Healing in a Murine Critical-Size Bone Defect Model
por: Tohidnezhad, Mersedeh, et al.
Publicado: (2020)

Different Frequency of Cyclic Tensile Strain Relates to Anabolic/Catabolic Conditions Consistent with Immunohistochemical Staining Intensity in Tenocytes
por: Kubo, Yusuke, et al.
Publicado: (2020)

Physiological Mineralization during In Vitro Osteogenesis in a Biomimetic Spheroid Culture Model
por: Koblenzer, Maximilian, et al.
Publicado: (2022)

Dehydroepiandrosterone modulates the inflammatory response in a bilateral femoral shaft fracture model
por: Lichte, Philipp, et al.
Publicado: (2014)

Platelet-Released Growth Factors and Platelet-Rich Fibrin Induce Expression of Factors Involved in Extracellular Matrix Organization in Human Keratinocytes
por: Bayer, Andreas, et al.
Publicado: (2020)

Impact of Uniaxial Stretching on Both Gliding and Traction Areas of Tendon Explants in a Novel Bioreactor
por: Tohidnezhad, Mersedeh, et al.
Publicado: (2020)

Actin filament content and organization in unstimulated platelets
Publicado: (1984)

Lipid metabolism of leukocytes in the unstimulated and activated states
por: Alarcon-Barrera, Juan Carlos, et al.
Publicado: (2020)

Unstimulated Gluteus Maximus Sphincteroplasty for Bowel Incontinence
por: Balakrishnan, Thalaivirithan Margabandu, et al.
Publicado: (2022)

Reference Gene Selection for Gene Expression Analyses in Mouse Models of Acute Lung Injury
por: Fragoulis, Athanassios, et al.
Publicado: (2021)

Nrf2 Is a Central Regulator of Metabolic Reprogramming of Myeloid-Derived Suppressor Cells in Steady State and Sepsis
por: Ohl, Kim, et al.
Publicado: (2018)

Nrf2 induces malignant transformation of hepatic progenitor cells by inducing β-catenin expression
por: Fragoulis, Athanassios, et al.
Publicado: (2022)

Enoxaparin Prevents Steroid-Related Avascular Necrosis of the Femoral Head
por: Beckmann, Rainer, et al.
Publicado: (2014)

Corrigendum to “Enoxaparin Prevents Steroid-Related Avascular Necrosis of the Femoral Head”
por: Beckmann, Rainer, et al.
Publicado: (2015)

UNSTIMULATED SECRETION OF PROTEIN FROM RAT EXOCRINE PANCREAS CELLS
por: Kramer, M. F., et al.
Publicado: (1972)

The Serine 814 of TRPC6 Is Phosphorylated under Unstimulated Conditions
por: Bousquet, Simon M., et al.
Publicado: (2011)

Long-term effect of tobacco on unstimulated salivary pH
por: Grover, Neeraj, et al.
Publicado: (2016)

Comparative analysis of bacterial profiles in unstimulated and stimulated saliva samples
por: Belstrøm, Daniel, et al.
Publicado: (2016)

Subjective sleep quality, unstimulated sexual arousal, and sexual frequency
por: Costa, Rui, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_356fl9kldtjb5b59o2vilu6vki