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Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation
INTRODUCTION: Systemic lupus erythematosus (SLE) is a T and B cell-dependent autoimmune disease characterized by the appearance of autoantibodies, a global regulatory T cells (Tregs) depletion and an increase in Th17 cells. Recent studies have shown the multifaceted immunomodulatory effects of vitam...
Autores principales: | Terrier, Benjamin, Derian, Nicolas, Schoindre, Yoland, Chaara, Wahiba, Geri, Guillaume, Zahr, Noël, Mariampillai, Kubéraka, Rosenzwajg, Michelle, Carpentier, Wassila, Musset, Lucile, Piette, Jean-Charles, Six, Adrien, Klatzmann, David, Saadoun, David, Patrice, Cacoub, Costedoat-Chalumeau, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580532/ https://www.ncbi.nlm.nih.gov/pubmed/23075451 http://dx.doi.org/10.1186/ar4060 |
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