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Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis

INTRODUCTION: Inflammatory arthritis is associated with increased bone resorption and suppressed bone formation. The Wnt antagonist dickkopf-1 (DKK1) is secreted by synovial fibroblasts in response to inflammation and this protein has been proposed to be a master regulator of bone remodelling in inf...

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Detalles Bibliográficos
Autores principales:	Hardy, Rowan, Juarez, Maria, Naylor, Amy, Tu, Jinwen, Rabbitt, Elizabeth H, Filer, Andrew, Stewart, Paul M, Buckley, Christopher D, Raza, Karim, Cooper, Mark S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580537/ https://www.ncbi.nlm.nih.gov/pubmed/23079210 http://dx.doi.org/10.1186/ar4065

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