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Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy

INTRODUCTION: Sjögren's syndrome (SjS) is a systemic autoimmune disease characterized by decreased salivary and lacrimal gland secretions, resulting in severe dry mouth and dry eyes. Recent studies have suggested that T(H)17 cells and its signature cytokine IL-17 are involved in the underlying...

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Detalles Bibliográficos
Autores principales: Lee, Byung Ha, Carcamo, Wendy C, Chiorini, John A, Peck, Ammon B, Nguyen, Cuong Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580566/
https://www.ncbi.nlm.nih.gov/pubmed/22827855
http://dx.doi.org/10.1186/ar3925