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Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy
INTRODUCTION: Sjögren's syndrome (SjS) is a systemic autoimmune disease characterized by decreased salivary and lacrimal gland secretions, resulting in severe dry mouth and dry eyes. Recent studies have suggested that T(H)17 cells and its signature cytokine IL-17 are involved in the underlying...
Autores principales: | Lee, Byung Ha, Carcamo, Wendy C, Chiorini, John A, Peck, Ammon B, Nguyen, Cuong Q |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580566/ https://www.ncbi.nlm.nih.gov/pubmed/22827855 http://dx.doi.org/10.1186/ar3925 |
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