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Abrogated RANKL expression in properdin-deficient mice is associated with better outcome from collagen-antibody-induced arthritis
INTRODUCTION: Properdin amplifies the alternative pathway of complement activation. In the present study, we evaluated its role in the development of collagen antibody-induced arthritis (CAIA). METHODS: Arthritis was induced by intraperitoneal injection of a collagen antibody cocktail into properdin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580567/ https://www.ncbi.nlm.nih.gov/pubmed/22830570 http://dx.doi.org/10.1186/ar3926 |