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Abrogated RANKL expression in properdin-deficient mice is associated with better outcome from collagen-antibody-induced arthritis

INTRODUCTION: Properdin amplifies the alternative pathway of complement activation. In the present study, we evaluated its role in the development of collagen antibody-induced arthritis (CAIA). METHODS: Arthritis was induced by intraperitoneal injection of a collagen antibody cocktail into properdin...

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Detalles Bibliográficos
Autores principales:	Dimitrova, Petya, Ivanovska, Nina, Belenska, Lyudmila, Milanova, Viktoriya, Schwaeble, Wilhelm, Stover, Cordula
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580567/ https://www.ncbi.nlm.nih.gov/pubmed/22830570 http://dx.doi.org/10.1186/ar3926

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