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Attenuation of osteoarthritis via blockade of the SDF-1/CXCR4 signaling pathway

INTRODUCTION: This study was performed to evaluate the attenuation of osteoarthritic (OA) pathogenesis via disruption of the stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine receptor type 4 (CXCR4) signaling with AMD3100 in a guinea pig OA model. METHODS: OA chondrocytes and cartilage explants...

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Detalles Bibliográficos
Autores principales:	Wei, Fangyuan, Moore, Douglas C, Li, Yanlin, Zhang, Ge, Wei, Xiaochun, Lee, Joseph K, Wei, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580571/ https://www.ncbi.nlm.nih.gov/pubmed/22849584 http://dx.doi.org/10.1186/ar3930

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