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Clinical and microbiological efficacy of continuous versus intermittent application of meropenem in critically ill patients: a randomized open-label controlled trial
INTRODUCTION: Meropenem bactericidal activity depends on the time when the free drug concentrations remain above the minimum inhibitory concentration of pathogens. The goal of this study was to compare clinical and bacteriological efficacy of continuous meropenem infusion versus bolus administration...
Autores principales: | Chytra, Ivan, Stepan, Martin, Benes, Jan, Pelnar, Petr, Zidkova, Alexandra, Bergerova, Tamara, Pradl, Richard, Kasal, Eduard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580671/ https://www.ncbi.nlm.nih.gov/pubmed/22742765 http://dx.doi.org/10.1186/cc11405 |
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