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A rapidly progressing lymphocyte exhaustion after severe sepsis
Septic syndromes induce immune alterations that have long been considered solely an overwhelming pro-inflammatory response. Increasing evidence now suggests that, after the first pro-inflammatory hours, sepsis is accompanied by the occurrence of a systemic immune failure. Here, novel perspectives re...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580699/ https://www.ncbi.nlm.nih.gov/pubmed/22824381 http://dx.doi.org/10.1186/cc11416 |
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author | Monneret, Guillaume Venet, Fabienne |
author_facet | Monneret, Guillaume Venet, Fabienne |
author_sort | Monneret, Guillaume |
collection | PubMed |
description | Septic syndromes induce immune alterations that have long been considered solely an overwhelming pro-inflammatory response. Increasing evidence now suggests that, after the first pro-inflammatory hours, sepsis is accompanied by the occurrence of a systemic immune failure. Here, novel perspectives regarding sepsis-induced lymphocyte alterations will be discussed in the context of a recently published study investigating overtime evolution of co-inhibitory lymphocyte receptor expressions in patients with severe sepsis. |
format | Online Article Text |
id | pubmed-3580699 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35806992013-07-23 A rapidly progressing lymphocyte exhaustion after severe sepsis Monneret, Guillaume Venet, Fabienne Crit Care Commentary Septic syndromes induce immune alterations that have long been considered solely an overwhelming pro-inflammatory response. Increasing evidence now suggests that, after the first pro-inflammatory hours, sepsis is accompanied by the occurrence of a systemic immune failure. Here, novel perspectives regarding sepsis-induced lymphocyte alterations will be discussed in the context of a recently published study investigating overtime evolution of co-inhibitory lymphocyte receptor expressions in patients with severe sepsis. BioMed Central 2012 2012-07-23 /pmc/articles/PMC3580699/ /pubmed/22824381 http://dx.doi.org/10.1186/cc11416 Text en Copyright ©2012 BioMed Central Ltd |
spellingShingle | Commentary Monneret, Guillaume Venet, Fabienne A rapidly progressing lymphocyte exhaustion after severe sepsis |
title | A rapidly progressing lymphocyte exhaustion after severe sepsis |
title_full | A rapidly progressing lymphocyte exhaustion after severe sepsis |
title_fullStr | A rapidly progressing lymphocyte exhaustion after severe sepsis |
title_full_unstemmed | A rapidly progressing lymphocyte exhaustion after severe sepsis |
title_short | A rapidly progressing lymphocyte exhaustion after severe sepsis |
title_sort | rapidly progressing lymphocyte exhaustion after severe sepsis |
topic | Commentary |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580699/ https://www.ncbi.nlm.nih.gov/pubmed/22824381 http://dx.doi.org/10.1186/cc11416 |
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