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Mild metabolic acidosis impairs the β-adrenergic response in isolated human failing myocardium

INTRODUCTION: Pronounced extracellular acidosis reduces both cardiac contractility and the β-adrenergic response. In the past, this was shown in some studies using animal models. However, few data exist regarding how the human end-stage failing myocardium, in which compensatory mechanisms are exhaus...

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Detalles Bibliográficos
Autores principales:	Schotola, Hanna, Toischer, Karl, Popov, Aron F, Renner, André, Schmitto, Jan D, Gummert, Jan, Quintel, Michael, Bauer, Martin, Maier, Lars S, Sossalla, Samuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580742/ https://www.ncbi.nlm.nih.gov/pubmed/22889236 http://dx.doi.org/10.1186/cc11468

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