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Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the “Missing Heritability” Problem

CYP3A4 is the most important drug metabolizing enzyme in adult humans because of its prominent expression in liver and gut and because of its broad substrate specificity, which includes drugs from most therapeutic categories and many endogenous substances. Expression and function of CYP3A4 vary exte...

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Detalles Bibliográficos
Autores principales:	Klein, Kathrin, Zanger, Ulrich M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580761/ https://www.ncbi.nlm.nih.gov/pubmed/23444277 http://dx.doi.org/10.3389/fgene.2013.00012

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