Rock1 & 2 Perform Overlapping and Unique Roles in Angiogenesis and Angiosarcoma Tumor Progression

The serine/threonine protein kinase paralogs ROCK1 & 2 have been implicated as essential modulators of angiogenesis; however their paralog-specific roles in endothelial function are unknown. shRNA knockdown of ROCK1 or 2 in endothelial cells resulted in a significant disruption of in vitro capil...

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Detalles Bibliográficos
Autores principales: Montalvo, J, Spencer, C, Hackathorn, A, Masterjohn, K, Perkins, A, Doty, C, Arumugam, A, Ongusaha, PP, Lakshmanaswamy, R, Liao, JK, Mitchell, DC, Bryan, BA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580831/
https://www.ncbi.nlm.nih.gov/pubmed/22934846
http://dx.doi.org/10.2174/1566524011307010205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3580831/
https://www.ncbi.nlm.nih.gov/pubmed/22934846
http://dx.doi.org/10.2174/1566524011307010205

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