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Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis

The primary objective of this study was to test the hypothesis that solid state fermentation (SSF) of agro-biomass (using rice straw as model); besides, breaking down its lignocellulose content to improve its nutritive values also produces lovastatin which could be used to suppress methanogenesis in...

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Autores principales: Faseleh Jahromi, Mohammad, Liang, Juan Boo, Mohamad, Rosfarizan, Goh, Yong Meng, Shokryazdan, Parisa, Ho, Yin Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581142/
https://www.ncbi.nlm.nih.gov/pubmed/23484116
http://dx.doi.org/10.1155/2013/397934
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author Faseleh Jahromi, Mohammad
Liang, Juan Boo
Mohamad, Rosfarizan
Goh, Yong Meng
Shokryazdan, Parisa
Ho, Yin Wan
author_facet Faseleh Jahromi, Mohammad
Liang, Juan Boo
Mohamad, Rosfarizan
Goh, Yong Meng
Shokryazdan, Parisa
Ho, Yin Wan
author_sort Faseleh Jahromi, Mohammad
collection PubMed
description The primary objective of this study was to test the hypothesis that solid state fermentation (SSF) of agro-biomass (using rice straw as model); besides, breaking down its lignocellulose content to improve its nutritive values also produces lovastatin which could be used to suppress methanogenesis in the rumen ecosystem. Fermented rice straw (FRS) containing lovastatin after fermentation with Aspergillus terreus was used as substrate for growth study of rumen microorganisms using in vitro gas production method. In the first experiment, the extract from the FRS (FRSE) which contained lovastatin was evaluated for its efficacy for reduction in methane (CH(4)) production, microbial population, and activity in the rumen fluid. FRSE reduced total gas and CH(4) productions (P < 0.01). It also reduced (P < 0.01) total methanogens population and increased the cellulolytic bacteria including Ruminococcus albus, Fibrobacter succinogenes (P < 0.01), and Ruminococcus flavefaciens (P < 0.05). Similarly, FRS reduced total gas and CH(4) productions, methanogens population, but increased in vitro dry mater digestibility compared to the non-fermented rice straw. Lovastatin in the FRSE and the FRS significantly increased the expression of HMG-CoA reductase gene that produces HMG-CoA reductase, a key enzyme for cell membrane production in methanogenic Archaea.
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spelling pubmed-35811422013-03-12 Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis Faseleh Jahromi, Mohammad Liang, Juan Boo Mohamad, Rosfarizan Goh, Yong Meng Shokryazdan, Parisa Ho, Yin Wan Biomed Res Int Research Article The primary objective of this study was to test the hypothesis that solid state fermentation (SSF) of agro-biomass (using rice straw as model); besides, breaking down its lignocellulose content to improve its nutritive values also produces lovastatin which could be used to suppress methanogenesis in the rumen ecosystem. Fermented rice straw (FRS) containing lovastatin after fermentation with Aspergillus terreus was used as substrate for growth study of rumen microorganisms using in vitro gas production method. In the first experiment, the extract from the FRS (FRSE) which contained lovastatin was evaluated for its efficacy for reduction in methane (CH(4)) production, microbial population, and activity in the rumen fluid. FRSE reduced total gas and CH(4) productions (P < 0.01). It also reduced (P < 0.01) total methanogens population and increased the cellulolytic bacteria including Ruminococcus albus, Fibrobacter succinogenes (P < 0.01), and Ruminococcus flavefaciens (P < 0.05). Similarly, FRS reduced total gas and CH(4) productions, methanogens population, but increased in vitro dry mater digestibility compared to the non-fermented rice straw. Lovastatin in the FRSE and the FRS significantly increased the expression of HMG-CoA reductase gene that produces HMG-CoA reductase, a key enzyme for cell membrane production in methanogenic Archaea. Hindawi Publishing Corporation 2013 2013-01-15 /pmc/articles/PMC3581142/ /pubmed/23484116 http://dx.doi.org/10.1155/2013/397934 Text en Copyright © 2013 Mohammad Faseleh Jahromi et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Faseleh Jahromi, Mohammad
Liang, Juan Boo
Mohamad, Rosfarizan
Goh, Yong Meng
Shokryazdan, Parisa
Ho, Yin Wan
Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title_full Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title_fullStr Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title_full_unstemmed Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title_short Lovastatin-Enriched Rice Straw Enhances Biomass Quality and Suppresses Ruminal Methanogenesis
title_sort lovastatin-enriched rice straw enhances biomass quality and suppresses ruminal methanogenesis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581142/
https://www.ncbi.nlm.nih.gov/pubmed/23484116
http://dx.doi.org/10.1155/2013/397934
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