Islet α-, β-, and δ-Cell Development Is Controlled by the Ldb1 Coregulator, Acting Primarily With the Islet-1 Transcription Factor

Ldb1 and Ldb2 are coregulators that mediate Lin11-Isl1-Mec3 (LIM)–homeodomain (HD) and LIM-only transcription factor–driven gene regulation. Although both Ldb1 and Ldb2 mRNA were produced in the developing and adult pancreas, immunohistochemical analysis illustrated a broad Ldb1 protein expression p...

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Detalles Bibliográficos
Autores principales: Hunter, Chad S., Dixit, Shilpy, Cohen, Tsadok, Ediger, Benjamin, Wilcox, Crystal, Ferreira, Mark, Westphal, Heiner, Stein, Roland, May, Catherine Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2013
Materias:
Islet Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581213/
https://www.ncbi.nlm.nih.gov/pubmed/23193182
http://dx.doi.org/10.2337/db12-0952

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