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Targeted Resequencing Reveals ALK Fusions in Non-Small Cell Lung Carcinomas Detected by FISH, Immunohistochemistry, and Real-Time RT-PCR: A Comparison of Four Methods

Anaplastic lymphoma receptor tyrosine kinase (ALK) gene rearrangements occur in a subgroup of non-small cell lung carcinomas (NSCLCs). The identification of these rearrangements is important for guiding treatment decisions. The aim of our study was to screen ALK gene fusions in NSCLCs and to compare...

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Detalles Bibliográficos
Autores principales: Tuononen, Katja, Sarhadi, Virinder Kaur, Wirtanen, Aino, Rönty, Mikko, Salmenkivi, Kaisa, Knuuttila, Aija, Remes, Satu, Telaranta-Keerie, Aino I., Bloor, Stuart, Ellonen, Pekka, Knuutila, Sakari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581296/
https://www.ncbi.nlm.nih.gov/pubmed/23484153
http://dx.doi.org/10.1155/2013/757490