Stimulation of Bone Formation in Cortical Bone of Mice Treated with a Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-binding Peptide That Possesses Osteoclastogenesis Inhibitory Activity

To date, parathyroid hormone is the only clinically available bone anabolic drug. The major difficulty in the development of such drugs is the lack of clarification of the mechanisms regulating osteoblast differentiation and bone formation. Here, we report a peptide (W9) known to abrogate osteoclast...

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Detalles Bibliográficos
Autores principales: Furuya, Yuriko, Inagaki, Atsushi, Khan, Masud, Mori, Kaoru, Penninger, Josef M., Nakamura, Midori, Udagawa, Nobuyuki, Aoki, Kazuhiro, Ohya, Keiichi, Uchida, Kohji, Yasuda, Hisataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581422/
https://www.ncbi.nlm.nih.gov/pubmed/23319583
http://dx.doi.org/10.1074/jbc.M112.426080

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