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Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies

Interferon alpha (IFNα) is used for the treatment of hepatitis C infection and whilst efficacious it is associated with multiple adverse events including reduced leukocyte, erythrocyte, and platelet counts, fatigue, and depression. These events are most likely caused by systemic exposure to interfer...

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Detalles Bibliográficos
Autores principales: Coulstock, Edward, Sosabowski, Jane, Ovečka, Milan, Prince, Rob, Goodall, Laura, Mudd, Clare, Sepp, Armin, Davies, Marie, Foster, Julie, Burnet, Jerome, Dunlevy, Gráinne, Walker, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581439/
https://www.ncbi.nlm.nih.gov/pubmed/23451195
http://dx.doi.org/10.1371/journal.pone.0057263