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Liver-Targeting of Interferon-Alpha with Tissue-Specific Domain Antibodies
Interferon alpha (IFNα) is used for the treatment of hepatitis C infection and whilst efficacious it is associated with multiple adverse events including reduced leukocyte, erythrocyte, and platelet counts, fatigue, and depression. These events are most likely caused by systemic exposure to interfer...
Autores principales: | Coulstock, Edward, Sosabowski, Jane, Ovečka, Milan, Prince, Rob, Goodall, Laura, Mudd, Clare, Sepp, Armin, Davies, Marie, Foster, Julie, Burnet, Jerome, Dunlevy, Gráinne, Walker, Adam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581439/ https://www.ncbi.nlm.nih.gov/pubmed/23451195 http://dx.doi.org/10.1371/journal.pone.0057263 |
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