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Lamin A/C Haploinsufficiency Modulates the Differentiation Potential of Mouse Embryonic Stem Cells

BACKGROUND: Lamins are structural proteins that are the major determinants of nuclear architecture and play important roles in various nuclear functions including gene regulation and cell differentiation. Mutations in the human lamin A gene cause a spectrum of genetic diseases that affect specific t...

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Detalles Bibliográficos
Autores principales:	Sehgal, Poonam, Chaturvedi, Pankaj, Kumaran, R. Ileng, Kumar, Satish, Parnaik, Veena K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581495/ https://www.ncbi.nlm.nih.gov/pubmed/23451281 http://dx.doi.org/10.1371/journal.pone.0057891

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