SGLT5 Reabsorbs Fructose in the Kidney but Its Deficiency Paradoxically Exacerbates Hepatic Steatosis Induced by Fructose

Although excessive fructose intake is epidemiologically linked with dyslipidemia, obesity, and diabetes, the mechanisms regulating plasma fructose are not well known. Cells transfected with sodium/glucose cotransporter 5 (SGLT5), which is expressed exclusively in the kidney, transport fructose in vi...

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Detalles Bibliográficos
Autores principales: Fukuzawa, Taku, Fukazawa, Masanori, Ueda, Otoya, Shimada, Hideaki, Kito, Aki, Kakefuda, Mami, Kawase, Yosuke, Wada, Naoko A., Goto, Chisato, Fukushima, Naoshi, Jishage, Kou-ichi, Honda, Kiyofumi, King, George L., Kawabe, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581502/
https://www.ncbi.nlm.nih.gov/pubmed/23451068
http://dx.doi.org/10.1371/journal.pone.0056681

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