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A cis-Acting Element Present within the gag Open Reading Frame Negatively Impacts on the Activity of the HIV-1 IRES

Translation initiation from the human immunodeficiency virus type-1 (HIV-1) mRNA can occur through a cap or an IRES dependent mechanism. Cap-dependent translation initiation of the HIV-1 mRNA can be inhibited by the instability element (INS)-1, a cis-acting regulatory element present within the gag...

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Detalles Bibliográficos
Autores principales:	Valiente-Echeverría, Fernando, Vallejos, Maricarmen, Monette, Anne, Pino, Karla, Letelier, Alejandro, Huidobro-Toro, J. Pablo, Mouland, Andrew J., López-Lastra, Marcelo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581557/ https://www.ncbi.nlm.nih.gov/pubmed/23451120 http://dx.doi.org/10.1371/journal.pone.0056962

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