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Epigenetic Control of Female Puberty
The timing of puberty is controlled by many genes. The elements coordinating this process have not, however, been identified. Here we show that an epigenetic mechanism of transcriptional repression times the initiation of female puberty in rats. We identify silencers of the Polycomb group (PcG) as m...
Autores principales: | Lomniczi, Alejandro, Loche, Alberto, Castellano, Juan Manuel, Ronnekleiv, Oline K., Bosch, Martha, Kaidar, Gabi, Knoll, J. Gabriel, Wright, Hollis, Pfeifer, Gerd. P., Ojeda, Sergio R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581714/ https://www.ncbi.nlm.nih.gov/pubmed/23354331 http://dx.doi.org/10.1038/nn.3319 |
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