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Ratio of Aβ42/P-tau(181p) in CSF is associated with aberrant default mode network in AD

The default mode network (DMN) is particularly relevant to Alzheimer's disease (AD) since its structures are vulnerable to deposition of amyloid. Decreased levels of β-amyloid(1-42) (Aβ42) and increased total tau protein (T-tau) and tau phosphorylated at position threonine 181 (P-tau(181p)) in...

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Detalles Bibliográficos
Autores principales: Li, Xiaozhen, Li, Tie-Qiang, Andreasen, Niels, Wiberg, Maria Kristoffersen, Westman, Eric, Wahlund, Lars-Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581831/
https://www.ncbi.nlm.nih.gov/pubmed/23439248
http://dx.doi.org/10.1038/srep01339

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