Cargando…

Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?

Background. Behcet's disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no...

Descripción completa

Detalles Bibliográficos
Autores principales: Cebeci, Filiz, Onsun, Nahide, Pekdemir, Ayşe, Uras, Ahmet R., Kayataş, Kadir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582163/
https://www.ncbi.nlm.nih.gov/pubmed/23476155
http://dx.doi.org/10.1155/2013/956837
_version_ 1782260546464120832
author Cebeci, Filiz
Onsun, Nahide
Pekdemir, Ayşe
Uras, Ahmet R.
Kayataş, Kadir
author_facet Cebeci, Filiz
Onsun, Nahide
Pekdemir, Ayşe
Uras, Ahmet R.
Kayataş, Kadir
author_sort Cebeci, Filiz
collection PubMed
description Background. Behcet's disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no controlled study is present in the PubMed, which evaluates thyroidal autoimmunity using antithyroid peroxidase antibody in a large series of patients with BD. Methods. We aimed to investigate the frequency of ATD in patients with BD. The study included 124 patients with BD and 99 age- and sex-matched healthy volunteers. Results. Autoimmune thyroiditis was noted in 21 cases (16.9%) with BD. In the control group, 22 cases (22.22%) were diagnosed as autoimmune thyroiditis. There was no difference between the groups in respect to thyroid autoantibodies (P > 0.05). There were no statistically significant differences between baseline TSH levels of the BD patients and of the controls (P > 0.05). Statistically, the mean serum free T4 levels of the patients with BD were higher than those of the controls (P < 0.001). Conclusions. No association could be found between BD and ATD. Therefore, it is not of significance to investigate thyroid autoimmunity in BD.
format Online
Article
Text
id pubmed-3582163
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-35821632013-03-09 Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association? Cebeci, Filiz Onsun, Nahide Pekdemir, Ayşe Uras, Ahmet R. Kayataş, Kadir ScientificWorldJournal Clinical Study Background. Behcet's disease (BD) could be regarded as an autoimmune disease in many aspects. Autoimmune thyroid disease (ATD) is frequently accompanied by other various autoimmune diseases. Nevertheless, there is not still enough data showing the association between BD and ATD. In addition, no controlled study is present in the PubMed, which evaluates thyroidal autoimmunity using antithyroid peroxidase antibody in a large series of patients with BD. Methods. We aimed to investigate the frequency of ATD in patients with BD. The study included 124 patients with BD and 99 age- and sex-matched healthy volunteers. Results. Autoimmune thyroiditis was noted in 21 cases (16.9%) with BD. In the control group, 22 cases (22.22%) were diagnosed as autoimmune thyroiditis. There was no difference between the groups in respect to thyroid autoantibodies (P > 0.05). There were no statistically significant differences between baseline TSH levels of the BD patients and of the controls (P > 0.05). Statistically, the mean serum free T4 levels of the patients with BD were higher than those of the controls (P < 0.001). Conclusions. No association could be found between BD and ATD. Therefore, it is not of significance to investigate thyroid autoimmunity in BD. Hindawi Publishing Corporation 2013-02-07 /pmc/articles/PMC3582163/ /pubmed/23476155 http://dx.doi.org/10.1155/2013/956837 Text en Copyright © 2013 Filiz Cebeci et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Cebeci, Filiz
Onsun, Nahide
Pekdemir, Ayşe
Uras, Ahmet R.
Kayataş, Kadir
Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title_full Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title_fullStr Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title_full_unstemmed Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title_short Thyroid Autoimmunity and Behçet's Disease: Is There a Significant Association?
title_sort thyroid autoimmunity and behçet's disease: is there a significant association?
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582163/
https://www.ncbi.nlm.nih.gov/pubmed/23476155
http://dx.doi.org/10.1155/2013/956837
work_keys_str_mv AT cebecifiliz thyroidautoimmunityandbehcetsdiseaseisthereasignificantassociation
AT onsunnahide thyroidautoimmunityandbehcetsdiseaseisthereasignificantassociation
AT pekdemirayse thyroidautoimmunityandbehcetsdiseaseisthereasignificantassociation
AT urasahmetr thyroidautoimmunityandbehcetsdiseaseisthereasignificantassociation
AT kayataskadir thyroidautoimmunityandbehcetsdiseaseisthereasignificantassociation