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ViralFusionSeq: accurately discover viral integration events and reconstruct fusion transcripts at single-base resolution

Summary: Insertional mutagenesis from virus infection is an important pathogenic risk for the development of cancer. Despite the advent of high-throughput sequencing, discovery of viral integration sites and expressed viral fusion events are still limited. Here, we present ViralFusionSeq (VFS), whic...

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Detalles Bibliográficos
Autores principales: Li, Jing-Woei, Wan, Raymond, Yu, Chi-Shing, Co, Ngai Na, Wong, Nathalie, Chan, Ting-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582262/
https://www.ncbi.nlm.nih.gov/pubmed/23314323
http://dx.doi.org/10.1093/bioinformatics/btt011