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Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008
BACKGROUND: Enteric pathogens are an important cause of illness, however, little is known about their community-level risk factors (e.g., socioeconomic, cultural and physical environmental conditions) in the Northwest Territories (NWT) of Canada. The objective of this study was to undertake ecologic...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582459/ https://www.ncbi.nlm.nih.gov/pubmed/23339723 http://dx.doi.org/10.1186/1471-2458-13-63 |
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author | Pardhan-Ali, Aliya Wilson, Jeff Edge, Victoria L Furgal, Chris Reid-Smith, Richard Santos, Maria McEwen, Scott A |
author_facet | Pardhan-Ali, Aliya Wilson, Jeff Edge, Victoria L Furgal, Chris Reid-Smith, Richard Santos, Maria McEwen, Scott A |
author_sort | Pardhan-Ali, Aliya |
collection | PubMed |
description | BACKGROUND: Enteric pathogens are an important cause of illness, however, little is known about their community-level risk factors (e.g., socioeconomic, cultural and physical environmental conditions) in the Northwest Territories (NWT) of Canada. The objective of this study was to undertake ecological (group-level) analyses by combining two existing data sources to examine potential community-level risk factors for campylobacteriosis, giardiasis and salmonellosis, which are three notifiable (mandatory reporting to public health authorities at the time of diagnosis) enteric infections. METHODS: The rate of campylobacteriosis was modeled using a Poisson distribution while rates of giardiasis and salmonellosis were modeled using a Negative Binomial distribution. Rate ratios (the ratio of the incidence of disease in the exposed group to the incidence of disease in the non-exposed group) were estimated for infections by the three major pathogens with potential community-level risk factors. RESULTS: Significant (p≤0.05) associations varied by etiology. There was increased risk of infection with Salmonella for communities with higher proportions of ‘households in core need’ (unsuitable, inadequate, and/or unaffordable housing) up to 42% after which the rate started to decrease with increasing core need. The risk of giardiasis was significantly higher both with increased ‘internal mobility’ (population moving between communities), and also where the community’s primary health facility was a health center rather than a full-service hospital. Communities with higher health expenditures had a significantly decreased risk of giardiasis. Results of modeling that focused on each of Giardia and Salmonella infections separately supported and expanded upon previous research outcomes that suggested health disparities are often associated with socioeconomic status, geographical and social mobility, as well as access to health care (e.g. facilities, services and professionals). In the campylobacteriosis model, a negative association was found between food prices in communities and risk of infection. There was also a significant interaction between trapping and consumption of traditional foods in communities. Higher rates of community participation in both activities appeared to have a protective effect against campylobacteriosis. CONCLUSIONS: These results raise very interesting questions about the role that traditional activities might play in infectious enteric disease incidence in the NWT, but should be interpreted with caution, recognizing database limitations in collection of case data and risk factor information (e.g. missing data). Given the cultural, socioeconomic, and nutritional benefits associated with traditional food practices, targeted community-based collaborative research is necessary to more fully investigate the statistical correlations identified in this exploratory research. This study demonstrates the value of examining the role of social determinants in the transmission and risk of infectious diseases. |
format | Online Article Text |
id | pubmed-3582459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-35824592013-02-27 Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 Pardhan-Ali, Aliya Wilson, Jeff Edge, Victoria L Furgal, Chris Reid-Smith, Richard Santos, Maria McEwen, Scott A BMC Public Health Research Article BACKGROUND: Enteric pathogens are an important cause of illness, however, little is known about their community-level risk factors (e.g., socioeconomic, cultural and physical environmental conditions) in the Northwest Territories (NWT) of Canada. The objective of this study was to undertake ecological (group-level) analyses by combining two existing data sources to examine potential community-level risk factors for campylobacteriosis, giardiasis and salmonellosis, which are three notifiable (mandatory reporting to public health authorities at the time of diagnosis) enteric infections. METHODS: The rate of campylobacteriosis was modeled using a Poisson distribution while rates of giardiasis and salmonellosis were modeled using a Negative Binomial distribution. Rate ratios (the ratio of the incidence of disease in the exposed group to the incidence of disease in the non-exposed group) were estimated for infections by the three major pathogens with potential community-level risk factors. RESULTS: Significant (p≤0.05) associations varied by etiology. There was increased risk of infection with Salmonella for communities with higher proportions of ‘households in core need’ (unsuitable, inadequate, and/or unaffordable housing) up to 42% after which the rate started to decrease with increasing core need. The risk of giardiasis was significantly higher both with increased ‘internal mobility’ (population moving between communities), and also where the community’s primary health facility was a health center rather than a full-service hospital. Communities with higher health expenditures had a significantly decreased risk of giardiasis. Results of modeling that focused on each of Giardia and Salmonella infections separately supported and expanded upon previous research outcomes that suggested health disparities are often associated with socioeconomic status, geographical and social mobility, as well as access to health care (e.g. facilities, services and professionals). In the campylobacteriosis model, a negative association was found between food prices in communities and risk of infection. There was also a significant interaction between trapping and consumption of traditional foods in communities. Higher rates of community participation in both activities appeared to have a protective effect against campylobacteriosis. CONCLUSIONS: These results raise very interesting questions about the role that traditional activities might play in infectious enteric disease incidence in the NWT, but should be interpreted with caution, recognizing database limitations in collection of case data and risk factor information (e.g. missing data). Given the cultural, socioeconomic, and nutritional benefits associated with traditional food practices, targeted community-based collaborative research is necessary to more fully investigate the statistical correlations identified in this exploratory research. This study demonstrates the value of examining the role of social determinants in the transmission and risk of infectious diseases. BioMed Central 2013-01-22 /pmc/articles/PMC3582459/ /pubmed/23339723 http://dx.doi.org/10.1186/1471-2458-13-63 Text en Copyright ©2013 Pardhan-Ali et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Pardhan-Ali, Aliya Wilson, Jeff Edge, Victoria L Furgal, Chris Reid-Smith, Richard Santos, Maria McEwen, Scott A Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title | Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title_full | Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title_fullStr | Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title_full_unstemmed | Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title_short | Community-level risk factors for notifiable gastrointestinal illness in the Northwest Territories, Canada, 1991-2008 |
title_sort | community-level risk factors for notifiable gastrointestinal illness in the northwest territories, canada, 1991-2008 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582459/ https://www.ncbi.nlm.nih.gov/pubmed/23339723 http://dx.doi.org/10.1186/1471-2458-13-63 |
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