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Carprofen for perioperative analgesia causes early anastomotic leakage in the rat ileum

BACKGROUND: There is increasing evidence that perioperative use of NSAIDs may compromise the integrity of intestinal anastomoses. This study aims to characterize the negative effects of carprofen on early anastomotic healing in the rat ileum. RESULTS: In 159 male Wistar rats an anastomosis was const...

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Detalles Bibliográficos
Autores principales: van der Vijver, Rozemarijn J, van Laarhoven, Cees JHM, Lomme, Roger MLM, Hendriks, Thijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582476/
https://www.ncbi.nlm.nih.gov/pubmed/23270317
http://dx.doi.org/10.1186/1746-6148-8-247

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