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Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner

BACKGROUND: Chromosome 17q21.31 contains a common inversion polymorphism of approximately 900 kb in populations with European ancestry. Two divergent MAPT haplotypes, H1 and H2 are described with distinct linkage disequilibrium patterns across the region reflecting the inversion status at this locus...

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Detalles Bibliográficos
Autores principales:	de Jong, Simone, Chepelev, Iouri, Janson, Esther, Strengman, Eric, van den Berg, Leonard H, Veldink, Jan H, Ophoff, Roel A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582489/ https://www.ncbi.nlm.nih.gov/pubmed/22950410 http://dx.doi.org/10.1186/1471-2164-13-458

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