Cargando…

Effect of NDP-α-MSH on PPAR-γ and –β Expression and Anti-Inflammatory Cytokine Release in Rat Astrocytes and Microglia

Brain inflammation plays a central role in numerous brain pathologies. Microglia and astrocytes are the main effector cells that become activated when an inflammatory process takes place within the central nervous system. α-melanocyte-stimulating hormone (α-MSH) is a neuropeptide with proven anti-in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Carniglia, Lila, Durand, Daniela, Caruso, Carla, Lasaga, Mercedes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582497/ https://www.ncbi.nlm.nih.gov/pubmed/23468969 http://dx.doi.org/10.1371/journal.pone.0057313

Ejemplares similares

Neuroinflammation in Huntington’s Disease: A Starring Role for Astrocyte and Microglia
por: Saba, Julieta, et al.
Publicado: (2022)

[Nle(4), D-Phe(7)]-α-MSH Inhibits Toll-Like Receptor (TLR)2- and TLR4-Induced Microglial Activation and Promotes a M2-Like Phenotype
por: Carniglia, Lila, et al.
Publicado: (2016)

Reduced cAMP, Akt Activation and p65-c-Rel Dimerization: Mechanisms Involved in the Protective Effects of mGluR3 Agonists in Cultured Astrocytes
por: Durand, Daniela, et al.
Publicado: (2011)

Astrocytes from cortex and striatum show differential responses to mitochondrial toxin and BDNF: implications for protection of striatal neurons expressing mutant huntingtin
por: Saba, Julieta, et al.
Publicado: (2020)

Alzheimer’s disease risk after COVID-19: a view from the perspective of the infectious hypothesis of neurodegeneration
por: Olivera, Eugenia, et al.
Publicado: (2022)

Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases
por: Carniglia, Lila, et al.
Publicado: (2017)

Interactions of the Melanocortin-4 Receptor with the Peptide Agonist NDP-MSH
por: Chapman, Kathryn L., et al.
Publicado: (2010)

Structures of active melanocortin-4 receptor–Gs-protein complexes with NDP-α-MSH and setmelanotide
por: Heyder, Nicolas A., et al.
Publicado: (2021)

Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γ Agonists
por: Gurley, Catherine, et al.
Publicado: (2008)

Presenilin 2 Is the Predominant γ-Secretase in Microglia and Modulates Cytokine Release
por: Jayadev, Suman, et al.
Publicado: (2010)

The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders
por: Porcuna, Jesús, et al.
Publicado: (2021)

Melanocortin receptor agonist NDP-α-MSH improves cognitive deficits and microgliosis but not amyloidosis in advanced stages of AD progression in 5XFAD and 3xTg mice
por: Daini, Eleonora, et al.
Publicado: (2023)

Comparison of PPAR Ligands as Modulators of Resolution of Inflammation, via Their Influence on Cytokines and Oxylipins Release in Astrocytes
por: Chistyakov, Dmitry V., et al.
Publicado: (2020)

PPAR-γ Impairment Alters Peroxisome Functionality in Primary Astrocyte Cell Cultures
por: Di Cesare Mannelli, Lorenzo, et al.
Publicado: (2014)

PPARα/γ-Independent Effects of PPARα/γ Ligands on Cysteinyl Leukotriene Production in Mast Cells
por: Yamashita, Masamichi
Publicado: (2008)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes
por: Rogue, Alexandra, et al.
Publicado: (2011)

Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors
por: Zhang, Li-Song, et al.
Publicado: (2012)

Immunomodulatory Effect of Microglia-Released Cytokines in Gliomas
por: Lanza, Marika, et al.
Publicado: (2021)

α-Melanocyte-stimulating-hormone (α-MSH) modulates human chondrocyte activation induced by proinflammatory cytokines
por: Capsoni, Franco, et al.
Publicado: (2015)

Regulation of melanophore stimulating hormone (MSH) release.
por: Hadley, M. E., et al.
Publicado: (1973)

MSH-release inhibiting factors: recent studies.
por: Kastin, A. J., et al.
Publicado: (1973)

Differential Induction of Proinflammatory Cytokines in Primary Mouse Astrocytes and Microglia by Coronavirus Infection
por: Yu, Dongdong, et al.
Publicado: (2006)

Cinnamein Inhibits the Induction of Nitric Oxide and Proinflammatory Cytokines in Macrophages, Microglia and Astrocytes
por: Pahan, Swarupa, et al.
Publicado: (2023)

Astrocyte—Microglia Interactions
por: BENVENISTE, ETTY N.
Publicado: (1993)

PPARγ and PPARα synergize to induce robust browning of white fat in vivo
por: Kroon, Tobias, et al.
Publicado: (2020)

A Role for PPARγ in the Regulation of Cytokines in Immune Cells and Cancer
por: Yang, Xiao Yi, et al.
Publicado: (2008)

Activation of the Melanocortin-1 Receptor by NDP-MSH Attenuates Oxidative Stress and Neuronal Apoptosis through PI3K/Akt/Nrf2 Pathway after Intracerebral Hemorrhage in Mice
por: Fu, Siming, et al.
Publicado: (2020)

Dual NDP52 Function in Persistent CSFV Infection
por: Fan, Shuangqi, et al.
Publicado: (2020)

NDP-related retinopathies: clinical phenotype of female carriers
por: Huang, Li, et al.
Publicado: (2023)

Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue
por: Ryu, Seung Lok, et al.
Publicado: (2013)

Microsecond MD Simulations to Explore the Structural and Energetic Differences between the Human RXRα-PPARγ vs. RXRα-PPARγ-DNA
por: Azam, Faizul, et al.
Publicado: (2022)

ATP Modifies the Proteome of Extracellular Vesicles Released by Microglia and Influences Their Action on Astrocytes
por: Drago, Francesco, et al.
Publicado: (2017)

PPAR α and PPAR γ Polymorphisms as risk factors for Dyslipidemia in a Chinese han population
por: Gu, Shu-Jun, et al.
Publicado: (2014)

MDG-1, a Potential Regulator of PPARα and PPARγ, Ameliorates Dyslipidemia in Mice
por: Wang, Xu, et al.
Publicado: (2017)

PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells
por: Karnati, Srikanth, et al.
Publicado: (2018)

PPARα and PPARγ activation is associated with pleural mesothelioma invasion but therapeutic inhibition is ineffective
por: Orozco Morales, M. Lizeth, et al.
Publicado: (2021)

NDP-MSH binding melanocortin-1 receptor ameliorates neuroinflammation and BBB disruption through CREB/Nr4a1/NF-κB pathway after intracerebral hemorrhage in mice
por: Wu, Xuan, et al.
Publicado: (2019)

Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With Neospora caninum
por: Argolo, Deivison Silva, et al.
Publicado: (2022)

Solution Structures of PPARγ2/RXRα Complexes
por: Osz, Judit, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_trbkcfusrvm900p3r0vmju059v