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Distinct Changes in Synaptic Protein Composition at Neuromuscular Junctions of Extraocular Muscles versus Limb Muscles of ALS Donors

The pathophysiology of amyotrophic lateral sclerosis (ALS) is very complex and still rather elusive but in recent years evidence of early involvement of the neuromuscular junctions (NMJs) has accumulated. We have recently reported that the human extraocular muscles (EOMs) are far less affected than...

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Detalles Bibliográficos
Autores principales: Liu, Jing-Xia, Brännström, Thomas, Andersen, Peter M., Pedrosa-Domellöf, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582511/
https://www.ncbi.nlm.nih.gov/pubmed/23468993
http://dx.doi.org/10.1371/journal.pone.0057473