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Preferential Duplication of Intermodular Hub Genes: An Evolutionary Signature in Eukaryotes Genome Networks

Whole genome protein-protein association networks are not random and their topological properties stem from genome evolution mechanisms. In fact, more connected, but less clustered proteins are related to genes that, in general, present more paralogs as compared to other genes, indicating frequent p...

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Detalles Bibliográficos
Autores principales: Ferreira, Ricardo M., Rybarczyk-Filho, José Luiz, Dalmolin, Rodrigo J. S., Castro, Mauro A. A., Moreira, José C. F., Brunnet, Leonardo G., de Almeida, Rita M. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582557/
https://www.ncbi.nlm.nih.gov/pubmed/23468868
http://dx.doi.org/10.1371/journal.pone.0056579