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High-Purity Preparation of HSV-2 Vaccine Candidate ACAM529 Is Immunogenic and Efficacious In Vivo
Genital herpes is a sexually transmitted infection (STI) caused by herpes simplex virus 2 (HSV-2) and to a lesser extent herpes simplex virus 1 (HSV-1). Infection by HSV-2 is life-long and is associated with significant cost to healthcare systems and social stigma despite the highly prevalent nature...
Autores principales: | Mundle, Sophia T., Hernandez, Hector, Hamberger, John, Catalan, John, Zhou, Changhong, Stegalkina, Svetlana, Tiffany, Andrea, Kleanthous, Harry, Delagrave, Simon, Anderson, Stephen F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582571/ https://www.ncbi.nlm.nih.gov/pubmed/23468943 http://dx.doi.org/10.1371/journal.pone.0057224 |
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