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New analogues of 13-hydroxyocatdecadienoic acid and 12-hydroxyeicosatetraenoic acid block human blood platelet aggregation and cyclooxygenase-1 activity

BACKGROUND: Thromboxane A(2) is derived from arachidonic acid through the action of cyclooxygenases and thromboxane synthase. It is mainly formed in blood platelets upon activation and plays an important role in aggregation. Aspirin is effective in reducing the incidence of complications following a...

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Detalles Bibliográficos
Autores principales:	Hirz, Taghreed, Khalaf, Ali, El-Hachem, Nehme, Mrad, May F, Abdallah, Hassan, Créminon, Christophe, Grée, René, Merhi, Raghida Abou, Habib, Aïda, Hachem, Ali, Hamade, Eva
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582601/ https://www.ncbi.nlm.nih.gov/pubmed/23228056 http://dx.doi.org/10.1186/1752-153X-6-152

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