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Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo

Malignant pleural mesothelioma (MPM) is an aggressive malignancy for which there is no approved targeted therapy. We examined the therapeutic efficacy of the mitogen-activated protein kinase kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) inhibitors against human MPM cell lines both in vitro a...

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Detalles Bibliográficos
Autores principales:	MIYOSHI, SEIGO, HAMADA, HIRONOBU, HAMAGUCHI, NAOHIKO, KATO, AKI, KATAYAMA, HITOSHI, IRIFUNE, KAZUNORI, ITO, RYOJI, MIYAZAKI, TATSUHIKO, OKURA, TAKAFUMI, HIGAKI, JITSUO
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582904/ https://www.ncbi.nlm.nih.gov/pubmed/22580933 http://dx.doi.org/10.3892/ijo.2012.1462

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