Extramammary Paget's Disease of External Genitalia with Bowenoid Features

Extramammary Paget's disease (EMPD) is an uncommon intraepithelial adenocarcinoma, primarily affecting the apocrine-bearing skin. Bowen disease is an intraepithelial squamous cell carcinoma having the potential to become invasive carcinoma. The histopathological concomitant features between EMP...

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Detalles Bibliográficos
Autores principales: Chung, Jimin, Kim, Jee Young, Gye, Jiwon, Namkoong, Sun, Hong, Seung Phil, Park, Byung Cheol, Kim, Myung Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Dermatological Association; The Korean Society for Investigative Dermatology 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582935/
https://www.ncbi.nlm.nih.gov/pubmed/23467383
http://dx.doi.org/10.5021/ad.2013.25.1.88
Descripción
Sumario:Extramammary Paget's disease (EMPD) is an uncommon intraepithelial adenocarcinoma, primarily affecting the apocrine-bearing skin. Bowen disease is an intraepithelial squamous cell carcinoma having the potential to become invasive carcinoma. The histopathological concomitant features between EMPD and Bowen disease have been described. One theory is that primary EMPD arises multicentrically, within the epidermis from the pluripotent stem cells. Herein, we describe a case of EMPD that had bowenoid features, and review the previous cases associated with the origin of EMPD.

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