Cargando…

Epimutation and cancer: A new carcinogenic mechanism of Lynch syndrome

Epimutation is defined as abnormal transcriptional repression of active genes and/or abnormal activation of usually repressed genes caused by errors in epigenetic gene repression. Epimutation arises in somatic cells and the germline, and constitutional epimutation may also occur. Epimutation is the...

Descripción completa

Detalles Bibliográficos
Autores principales: BANNO, KOUJI, KISU, IORI, YANOKURA, MEGUMI, TSUJI, KOSUKE, MASUDA, KENTA, UEKI, ARISA, KOBAYASHI, YUSUKE, YAMAGAMI, WATARU, NOMURA, HIROYUKI, TOMINAGA, EIICHIRO, SUSUMU, NOBUYUKI, AOKI, DAISUKE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582986/
https://www.ncbi.nlm.nih.gov/pubmed/22735547
http://dx.doi.org/10.3892/ijo.2012.1528