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Resistance to PARP-Inhibitors in Cancer Therapy

The pharmacological inhibitors of poly(ADP-ribose) polymerase (PARP) family of proteins have shown promising results in preclinical studies and clinical trials as a monotherapy or in combination therapy for some cancers. Thus, usage of PARP-inhibitors (PARPi) in cancer therapy is bound to increase w...

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Detalles Bibliográficos
Autores principales:	Montoni, Alicia, Robu, Mihaela, Pouliot, Émilie, Shah, Girish M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583007/ https://www.ncbi.nlm.nih.gov/pubmed/23450678 http://dx.doi.org/10.3389/fphar.2013.00018

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